Celiac Disease Research Center, Tampere, Finland; Central Finland Central Hospital, Jyväskylä, Finland
PhD Juha Taavela is post-doctoral researcher studying celiac disease and non-celiac gluten sensitivity at Celiac Disease Research Center in Tampere while specialising to internal medicine in Central Finland Central Hospital. He has been studying celiac disease since 2009 focusing on the reliability of celiac disease diagnostics, discovering new diagnostic markers in the small-bowel mucosa of celiac disease patients and participating as a clinical researcher in several celiac disease therapy trials. Currently his study aims at discovering the incidence, pathogenesis and prognosis of non-celiac gluten sensitivity in Finland.
Non-celiac gluten sensitivity is clinical syndrome characterized by various intestinal and extra-intestinal symptoms responsive to dietary gluten exclusion. An increasing number of people are self-diagnosing non-celiac gluten sensitivity, but the true incidence is unknown due to the lack of disease-specific diagnostic tests. An international expert statement suggests a 15-week placebo-controlled challenge trial for the diagnosis, but such trial is too burdensome for everyday clinical practise. Interestingly, it has been suggested that other components of wheat or poorly absorbed carbohydrates (“FODMAPs”) might be the actual or at least partial cause of the symptoms. Currently, the pathogenesis, prognosis and the required strictness of dietary restriction in gluten sensitivity are unclear.